Mk 677 (INN) (developmental code names MK-677, MK-0677, L-163,191; former tentative brand name Oratrope) is a potent, long-acting, orally active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been shown to increase the secretion of several hormones, including GH and insulin-like growth factor 1 (IGF-1) and produces sustained increases in the plasma levels of these hormones without affecting cortisol levels.
Ibutamoren has been shown to sustain activation of the GH–IGF-1 axis and to increase lean body mass with no change in total fat mass or visceral fat. It is under investigation as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising potential therapy for the treatment of frailty in the elderly. As of June 2017, ibutamoren is in the preclinical stage of development for growth hormone deficiency.
What Is Ibutamoren?
MK 677, or better known as Ibutamoren, is what we call a growth hormone secretagogue. You’ll find many people that refer to it as a selective androgen receptor modulator (SARM), but it isn’t really one.
The reason this research compound has gotten popular is that of its ability to enhance growth hormone levels and IGF-1.
That is also one of the major reasons it’s currently being used in research–to help treat reduced levels of these hormones.
But bodybuilders commonly used this compound. They use Ibutamoren to help enhance recovery, muscle mass and strength.
This all whilst having little to no side effects. It’s one of the very few compounds that actually can boost Human Growth Hormone (HGH).
In this article, we’re going to inspect this compound and if it’s actually worth using.
MK 677 (Ibutamoren) Benefits
Let’s start off by looking at the benefits you can expect from researching with MK 677. Keep in mind that it’s very important to have a legitimate source before researching with this product.
MK 677 Dosage Information
It’s obviously very important to know what the best MK 677 dosage is. I’ve done a lot of research on this compound and the optimal dosage is between 10 to 30mg per day.
I have personally researched with this compound and found 20mg per day to be the sweet spot. At this dosage, I started feeling the effects rather quickly. It is worth mentioning that I was using a high-quality source for this compound.