Nandrolone is also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin). Nandrolone esters are used in the treatment of anemias, cachexia (wasting syndrome), osteoporosis, breast cancer, and other indications. They are not used by mouth and instead are given by injection into muscle or fat.
Side effects of nandrolone esters include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire. They are synthetic androgens and anabolic steroids and hence are agonists of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT). Deca Durabolin esters have strong anabolic effects and weak androgenic effects, which give them a mild side effect profile and make them especially suitable for use in women and children. They are long-lasting prodrugs of nandrolone in the body.
Nandrolone esters were first described and introduced for medical use in the late 1950s. They are among the most widely used AAS worldwide. In addition to their medical use, nandrolone esters are used to improve physique and performance and are said to be the most widely used AAS for such purposes. Drugs are controlled substances in many countries and so non-medical use is generally illicit. Nandrolone esters are used clinically, although increasingly rarely, for people in catabolic states with major burns, cancer, and AIDS, and an ophthalmological formulation was available to support cornea healing.
These medicines help to rebuild tissues that have become weak because of continuing illness or serious injury. Deca-Durabolin can be used to increase lean body mass in the case of negative nitrogen balance. It can also be used to increase bone mass and stimulate the formation of red blood cells in the bone marrow.
• pain at the injection site
• fluid retention e.g. swelling of the
ankles or feet
• increased blood pressure
• oily skin, greasy hair
• acne, rash
• increased blood fats
• abnormal liver function
• increased or decreased sexually
• liver anatomy changes
• incomplete stature growth